Download the preliminary program outline
Symposium sessions, including confirmed speakers (to date):
| Higher order P450 structural biology: quaternary structures and metabolon formation | Interactions with redox partners | P450s in drug discovery pipelines (Industry Forum) |
| Prof Birger Lindberg Moller, University of Copenhagen, Denmark Dr Chang-Jun Liu, Brookhaven National Laboratory, USA |
Prof James Kincaid, Marquette University, USA Dr Ilia Denisov, University of Illinois, USA Prof Lucy Waskell, University of Michigan, USA |
Dr Scott Obach, Pfizer, USA Dr Mike Wester, Vertex, USA |
| Light-driven P450 catalysis |
P450s in vitro drug metabolism and pharmacokinetics | Extrahepatic P450s in health and disease |
| Prof Erik Jensen, University of Copenhagen, Denmark Assoc Prof Lionel Cheruzel, San Jose State University, USA Dr Chul-Ho Yun, Chonnam National University, South Korea |
Dr Hiroshi Yamazaki, Showa Pharmaceutical University, Japan Dr Ulrik Jurva, AstraZeneca R&D, USA Dr Andrew Parkinson, XPD Consulting, USA |
Assoc Prof Rheem Totah, University of Washington, USA Dr Andrew Rowland, Flinders University, Australia Prof Matthias Bureik,Tianjin University, China Dr XinXin Ding, The University of Arizona, USA |
| Mechanistic enzymology of P450s | Biophysical approaches to study P450s | Protein engineering for biocatalysis and biosensors |
| Speakers to be confirmed | Dr Beatrice Vallone, Istituto Pasteur-Fondazione Cenci Bolognetti, Italy Dr William Atkins, University of Washington, USA Prof Nitin Jain, University of Tennessee Knoxville, USA |
Prof Vlada Urlacher, University of Dusseldorf, Germany |
| Metabolic and process engineering of P450s for biotechnological applications | Approaches to understanding P450s in the “omics” era | Structural biology of P450s |
| Prof Sabine Flitsche, The University of Manchester, UK Assoc Prof Luet Wong, University of Oxford, UK |
Prof Fred Guengerich, Valderbilt University School of Medicine, USA Dr Jed Goldstone, Woods Hole Oceanographic Institution, USA |
Prof Eric Johnson, Scripps Research, USA Dr Emily Scott, University of Michigan, USA |
| Regulation of P450s gene expression: natural and artificial | Reactive metabolites and adverse reactions: P450s in molecular toxicology | P450 evolution and biodiversity |
| Prof Eddie Morgan, Emory University, USA Dr Frank Gonzalez, National Cancer Institute, USA |
Dr Amit Kalgutkar, Pfizer, USA Prof Ana Alfirevic, University of Liverpool, UK Dr Irina Pikuleva, Case Western Reserve University, USA |
Speakers to be confirmed |
| Steroids across the biosphere | Plant P450s in the biosynthesis of terpenoids and other interesting secondary metabolites | P450s in plant-insect ecology and the future of pesticides |
| Prof Rita Bernhardt, Saarland University, Germany Prof Ric Auchus, University of Michigan, USA |
Dr Shingo Nagano, Tottori University Graduate School of Engineering, Japan | Prof Steven Powles, University of Western Australia, Australia |
| Novel chemistry of P4XX (or when is a P450, not a P450? | Mining the (micro)biome: novel P450s from the (micro) biosphere | Molecular modelling of P450 systems |
| Dr Shengying Li, Chinese Academy of Sciences, China |
Prof Andrew Munro, The University of Manchester, UK Prof Greg Challis, Warwick University, UK |
Dr Rebecca Wade, Heidelberg Institute for Theoretical Studies, Germany Prof John Hackett, Virginia Commonwealth University, USA |