Download the preliminary program outline
Symposium sessions, including confirmed speakers (to date):
| Higher order structural biology of P450s – metabolon formation | Interactions with redox partners | P450s in drug discovery pipelines (Industry Forum) |
| Birger Lindberg Moller, University of Copenhagen, Denmark Ilia Denisov, University of Illinois, USA Max Cryle, Monash University, Australia |
James Kincaid, Marquette University, USA Stephen Bell, University of Adelaide, Australia Gilles Truan, Institut National des Sciences Appliquées de Toulouse, France Ilia Denisov, University of Illinois, USA |
Scott Obach, Pfizer, USA Mike Wester, Vertex, USA Griffith Humphreys, USA |
| Light-driven catalysis and other novel ways to support P450s |
P450s in in vitro drug metabolism and pharmacokinetics | Extrahepatic P450s in health and disease |
| Poul-Erik Jensen, University of Copenhagen, Denmark Prof Lionel Cheruzel, San Jose State University, USA Chul-Ho Yun, Chonnam National University, South Korea |
Hiroshi Yamazaki, Showa Pharmaceutical University, Japan Ulrik Jurva, AstraZeneca R&D, USA Andrew Parkinson, XPD Consulting, USA James Halpert, University of Connecticut, USA Eric Chan, National University of Singapore, Singapore |
Rheem Totah, University of Washington, USA Andrew Rowland, Flinders University, Australia Matthias Bureik,Tianjin University, China |
| Mechanistic enzymology of P450s | Biophysical approaches to studying P450 conformational dynamics |
Protein engineering for biocatalysis and biosensors |
| James de Voss, The University of Queensland, Australia Thomas Pochapsky, Brandeis University, USA Kshatresh Dutta Dubey, Shiv Nadar University, India |
Beatrice Vallone, Istituto Pasteur-Fondazione Cenci Bolognetti, Italy William Atkins, University of Washington, USA Nitin Jain, University of Tennessee Knoxville, USA Haoming Zhang, University of Michigan, USA |
Vlada Urlacher, University of Dusseldorf, Germany Osami Shoji, Nagoya University, Japan Luet Wong, University of Oxford, UK |
| Metabolic and process engineering of P450s for biotechnological applications | Looking to the future: understanding P450 “omics” in the era | Structural biology of P450s |
| Sabine Flitsche, The University of Manchester, UK Gianfranco Gilardi, University of Turin, Italy Anton Glieder, Graz University Of Technology, Austria Volker Sieber, Technical University of Munich, Germany Wenhai Xiao, Tianjin University, China |
Sarah Glass, Vanderbilt University School of Medicine, USA Rochelle Soo, The University of Queensland, Australia |
Eric Johnson, Scripps Research, USA Emily Scott, University of Michigan, USA Irina Sevrioukova, University of California Irvine, USA |
| Regulation of P450s gene expression: natural and artificial | Reactive metabolites and adverse reactions: P450s in molecular toxicology | Evolution and biodiversity |
| Eddie Morgan, Emory University, USA John Dawson, University of South Carolina, USA |
Amit Kalgutkar, Pfizer, USA Ana Alfirevic, University of Liverpool, UK XinXin Ding, The University of Arizona, USA |
Elizabeth Gilliam, The University of Queensland, Australia Catherine Grueber, Koala Genome Project, Australia Galina Lepesheva, Vanderbilt University School of Medicine, USA |
| Steroids across the biosphere | Plant P450s in the biosynthesis of terpenoids and other interesting secondary metabolites | P450s in plant-insect ecology and the future of pesticides |
| Rita Bernhardt, Saarland University, Germany Ric Auchus, University of Michigan, USA Amanda Swart, University of Stellenbosch, South Africa |
Shingo Nagano, Tottori University Graduate School of Engineering, Japan Mette Sorensen, University of Copenhagen, Denmark |
Heping Han, University of Western Australia, Australia David Heckel, Max Planck Institute for Chemical Ecology, Germany Phil Batterham, The University of Melbourne, Australia |
| Novel P450 chemistry – when is a P450 not a P450? | Mining the (micro)biome: novel P450s from the (micro) biosphere | Molecular modelling of P450 systems |
| Shengying Li, Chinese Academy of Sciences, China |
Andrew Munro, The University of Manchester, UK Greg Challis, Warwick University, UK |
Rebecca Wade, Heidelberg Institute for Theoretical Studies, Germany John Hackett, Virginia Commonwealth University, USA Pramod Nair, Flinders University, Australia |
| Sterol-metabolising P450s in health and disease | ||
| Robert Tuckey, The University of Western Australia, Australia Irina Pikuleva, Case Western Reserve University, USA Toshiyuki Sakaki, Toyama Prefectural University, Japan |